-2(x + 5 × 7 + 3)

Simplfy -2(x + 5 × 7 + 3).

Or Simplify -2(x+5*7+3) . The editted form is due to me please.

To simplify we apply the BODMAS( Bracket, Order(means degree or exponent), Division or Multiplication with equal prioriy, Addtion or Subtraction with equal priority), the rule of priority  here.

In the given problem, Bracket is first.Inside the bracket Multiplication is first:

So, in the expression,-2(x+5*7+3), take the bracket first. And in the bracket ,inside, Multiplication  of 5*7 is first:

-2(x+35+3).

Simplify inside the bracket: 35+3 =38:

-2(x+38).

Multiply by -2 of outside the bracket each of the terms  inside the bracket. This is to say to distribute the operation of mutiplication over the two terms inside the bracket, keeping in mind the rule of sign of two terms with different sign(+or-) in multiplication  returning a negative product.

-2x-76 and this is the final simplest form.

Hope this would help.